Discovery of adamantane based highly potent HDAC inhibitors

Discovery of adamantane based highly potent HDAC inhibitors Identification of novel HDAC inhibitors through cell based screening and their evaluation as potential anticancer agents Influence of the adamantyl moiety on the activity of biphenylacrylohydroxamic acid-based HDAC inhibitors Development of 3-hydroxycinnamamide-based HDAC inhibitors with potent in vitro and in vivo anti-tumor activity Design, synthesis and evaluation of novel HDAC inhibitors as potential antitumor agents Selective HDAC inhibitors with potent oral activity against leukemia and colorectal cancer: Design, structure-activity relationship and anti-tumor activity study 4-Indolyl- N -hydroxyphenylacrylamides as potent HDAC class I and IIB inhibitors in vitro and in vivo Design, synthesis and activity evaluation of indole-based double – Branched HDAC1 inhibitors Novel amide derivatives as inhibitors of histone deacetylase: Design, synthesis and SAR Design, synthesis and preliminary biological evaluation of indoline-2,3-dione derivatives as novel HDAC inhibitors