Discovery of the First Histone Deacetylase 6/8 Dual Inhibitors

Discovery of the First Histone Deacetylase 6/8 Dual Inhibitors Potent and Selective Inhibition of Histone Deacetylase 6 (HDAC6) Does Not Require a Surface-Binding Motif Design, Synthesis, and Pharmacological Evaluation of NovelN-Acylhydrazone Derivatives as Potent Histone Deacetylase 6/8 Dual Inhibitors Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs) Molecular Basis for the Selective Inhibition of Histone Deacetylase 6 by a Mercaptoacetamide Inhibitor Design and Synthesis of Orally Bioavailable Aminopyrrolidinone Histone Deacetylase 6 Inhibitors Synthesis and Biological Investigation of Oxazole Hydroxamates as Highly Selective Histone Deacetylase 6 (HDAC6) Inhibitors Diphenylmethylene hydroxamic acids as selective class IIa histone deacetylase inhibitors Potent Histone Deacetylase Inhibitors Derived from 4-(Aminomethyl)-N-hydroxybenzamide with High Selectivity for the HDAC6 Isoform Development of a Potent and Selective HDAC8 Inhibitor