New phenstatin–fatty acid conjugates: Synthesis and evaluation

Bioorganic & Medicinal Chemistry Letters
2013.0

Abstract

New phenstatin-fatty acid conjugates have been synthesized and tested against the KB-3-1, H460, MCF-7 and HEK293 cell lines, with an increase in anti-proliferative activity being observed at the micro-molar level paralleling an increase in un-saturation in the fatty acid component.

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