Identification of ML251, a Potent Inhibitor ofT. brucei and T. cruziPhosphofructokinase

Identification of ML251, a Potent Inhibitor ofT. brucei and T. cruziPhosphofructokinase Pharmacological Validation of Trypanosoma brucei Phosphodiesterases B1 and B2 as Druggable Targets for African Sleeping Sickness Catechol Pyrazolinones as Trypanocidals: Fragment-Based Design, Synthesis, and Pharmacological Evaluation of Nanomolar Inhibitors of Trypanosomal Phosphodiesterase B1 Inhibition ofTrypanosomacruziHexokinase by Bisphosphonates Antitrypanosomal alkaloids from Polyalthia suaveolens (Annonaceae): Their effects on three selected glycolytic enzymes of Trypanosoma brucei Discovery of a Novel Class of Orally Active Trypanocidal N-Myristoyltransferase Inhibitors Identification of novel inhibitors of UDP-Glc 4′-epimerase, a validated drug target for african sleeping sickness Antitrypanosomal alkaloids from Polyalthia suaveolens (Annonaceae): Their effects on three selected glycolytic enzymes of Trypanosoma brucei Discovery and antiparasitic activity of AZ960 as a Trypanosoma brucei ERK8 inhibitor Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity