Potent Hepatitis C Virus NS5A Inhibitors Containing a Benzidine Core

Potent Hepatitis C Virus NS5A Inhibitors Containing a Benzidine Core Synthesis and evaluation of novel potent HCV NS5A inhibitors Discovery and Characterization of Potent Pan-Genotypic HCV NS5A Inhibitors Containing Novel Tricyclic Central Core Leading to Clinical Candidate Synthesis and evaluation of non-dimeric HCV NS5A inhibitors 4-(1,1-Dioxo-1,4-dihydro-1λ6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase New potent biaryl sulfate-based hepatitis C virus inhibitors Hexahydro-pyrrolo- and hexahydro-1H-pyrido[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase Allosteric inhibitors of hepatitis C virus NS5B polymerase thumb domain site II: Structure-based design and synthesis of new templates Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 5: Exploration of pyridazinones containing 6-amino-substituents Discovery of a series of novel compounds with moderate anti-hepatitis C virus NS3 protease activity in vitro