Facile synthesis of a polyether-tethered dimeric berberine as a highly effective DNA-cleaving agent in the presence of Cu(ii) ion

Facile synthesis of a polyether-tethered dimeric berberine as a highly effective DNA-cleaving agent in the presence of Cu(ii) ion Synthesis of 10-O-aryl-substituted berberine derivatives by Chan–Evans–Lam coupling and investigation of their DNA-binding properties Resveratrol as a new type of DNA-cleaving agent Synthesis and DNA-binding affinities of monomodified berberines Synthesis, structure and DNA cleavage studies of coumarin analogues of tetrahydroisoquinoline and protoberberine alkaloids RhIII-catalyzed synthesis and investigation of the DNA-binding properties of 11- and 13-substituted berberine derivatives Discovery of novel berberine imidazoles as safe antimicrobial agents by down regulating ROS generation Synthesis and investigation of quadruplex-DNA-binding, 9-O-substituted berberine derivatives Synthesis and investigation of quadruplex-DNA-binding, 9-O-substituted berberine derivatives Novel benzimidazolyl tetrahydroprotoberberines: Design, synthesis, antimicrobial evaluation and multi-targeting exploration