Synthetic metabolites of neurohypophyseal hormones. [Des-9-glycinamide]oxytocin and [des-9-glycinamide,des-8-leucine]oxytocin

Synthetic metabolites of neurohypophyseal hormones. [Des-9-glycinamide]oxytocin and [des-9-glycinamide,des-8-leucine]oxytocin Oxytocin and lysine-vasopressin with N5,N5-dialkylglutamine in the 4 position: effect of introducing sterically hindered groups into the hydrophilic cluster of neurohypophyseal hormones Combined high oxytocic with negligible antidiuretic and pressor activities in multisubstituted oxytocins Oxytocin analogues with combined high smooth muscle and negligible antidiuretic activities. Investigation of position 7 in neurohypophyseal hormones Synthesis and biological activity of oxytocin analogues containing conformationally-restricted residues in position 7 Synthesis and some pharmacological properties of oxytocin and vasopressin analogs with sarcosine or N-methyl-L-alanine in position 7 Replacement of the disulfide bond in oxytocin by an amide group. Synthesis and some biological properties of [cyclo-(1-L-aspartic acid, 6-L-.alpha.,.beta.-diaminopropionic acid)]oxytocin Synthesis and some pharmacological properties of [4-threonine,7-glycine]oxytocin, [1-(L-2-hydroxy-3-mercaptopropanoic acid),4-threonine,7-glycine]oxytocin (hydroxy[thr4, gly7]oxytocin), and [7-glycine]oxytocin, peptides with high oxytocic-antidiuretic selectivity [1-Penicillamine,2-leucine]oxytocin. Synthesis and pharmacological and conformational studies of a potent peptide hormone inhibitor Synthesis and some pharmacological properties of [4-threonine,7-sarcosine]oxytocin, a peptide with high oxytocic potency, and of [4-threonine,7-N-methylalanine]oxytocin