Discovery of novel pyrimidine and malonamide derivatives as TGR5 agonists

Discovery of novel pyrimidine and malonamide derivatives as TGR5 agonists Novel Potent and Selective Bile Acid Derivatives as TGR5 Agonists: Biological Screening, Structure−Activity Relationships, and Molecular Modeling Studies Design and synthesis of novel pyrimido[5,4-d]pyrimidine derivatives as GPR119 agonist for treatment of type 2 diabetes Design and biological evaluation of tetrahydropyridine derivatives as novel human GPR119 agonists Structure−Activity Relationship Study of Betulinic Acid, A Novel and Selective TGR5 Agonist, and Its Synthetic Derivatives: Potential Impact in Diabetes Hit-to-Lead Optimization of Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists with a Diphenylmethane-Scaffold: Design, Synthesis, and Biological Study 7-Methylation of Chenodeoxycholic Acid Derivatives Yields a Substantial Increase in TGR5 Receptor Potency Novel 5-nitropyrimidine derivatives bearing endo-azabicyclic alcohols/amines as potent GPR119 agonists Discovery of 2H-Chromen-2-one Derivatives as G Protein-Coupled Receptor-35 Agonists Design, synthesis and biological evaluation of a series of novel GPR40 agonists containing nitrogen heterocyclic rings