Structure–Activity Relationship Studies of a Series of Semisynthetic Lipopeptides Leading to the Discovery of Surotomycin, a Novel Cyclic Lipopeptide Being Developed for the Treatment of Clostridium difficile-Associated Diarrhea

Structure–Activity Relationship Studies of a Series of Semisynthetic Lipopeptides Leading to the Discovery of Surotomycin, a Novel Cyclic Lipopeptide Being Developed for the Treatment of Clostridium difficile-Associated Diarrhea Discovery and development of surotomycin for the treatment of <i>Clostridium difficile</i> Structure–Activity Relationships of Daptomycin Lipopeptides Genetically Engineered Lipopeptide Antibiotics Related to A54145 and Daptomycin with Improved Properties Semisynthetic Approaches to Laspartomycin Analogues Synthesis and Bioactivity Investigation of the Individual Components of Cyclic Lipopeptide Antibiotics Structural Characterization of Daptomycin Analogues A21978C_1-3(<scp>d</scp>-Asn₁₁) Produced by a Recombinant <i>Streptomyces roseosporus</i> Strain Structural Characterization of Daptomycin Analogues A21978C_1-3(<scp>d</scp>-Asn₁₁) Produced by a Recombinant <i>Streptomyces roseosporus</i> Strain Antimicrobial Peptides with Potential for Biofilm Eradication: Synthesis and Structure Activity Relationship Studies of Battacin Peptides Synthesis and Structure–Activity Relationship Studies of N-Terminal Analogues of the Antimicrobial Peptide Tridecaptin A₁