Novel antibacterial active quinolone–fluoroquinolone conjugates and 2D-QSAR studies

Bioorganic & Medicinal Chemistry Letters
2015.0

Abstract

Novel, quinolone-fluoroquinolone conjugates 10a-f, 11a-f, 13a-f and 14a-f with amino acid linkers were synthesized in good yields utilizing benzotriazole chemistry. Antibacterial bioassay showed the synthesized bis-conjugates exhibit anti-bacterial properties comparable with the parent drugs.

Knowledge Graph

Similar Paper