Primaquine–pyrimidine hybrids: Synthesis and dual-stage antiplasmodial activity

European Journal of Medicinal Chemistry
2015.0

Abstract

A series of novel pyrimidine-primaquine hybrids were synthesized and their effectiveness against the blood and liver stages of malaria parasites was evaluated. The hybrids displayed enhanced liver stage in vitro activity against P. berghei liver stage infection.

Knowledge Graph

Similar Paper