Identification of a potent inhibitor targeting human lactate dehydrogenase A and its metabolic modulation for cancer cell line

Identification of a potent inhibitor targeting human lactate dehydrogenase A and its metabolic modulation for cancer cell line Development of novel human lactate dehydrogenase A inhibitors: High-throughput screening, synthesis, and biological evaluations Discovery of human lactate dehydrogenase A (LDHA) inhibitors as anticancer agents to inhibit the proliferation of MG-63 osteosarcoma cells Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells Design and Synthesis of Novel Lactate Dehydrogenase A Inhibitors by Fragment-Based Lead Generation Recent Update on Human Lactate Dehydrogenase Enzyme 5 (hLDH5) Inhibitors: A Promising Approach for Cancer Chemotherapy Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism Fragment Growing and Linking Lead to Novel Nanomolar Lactate Dehydrogenase Inhibitors Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase Small molecule cores demonstrate non-competitive inhibition of lactate dehydrogenase