Synthesis of indole-derived allocolchicine congeners exhibiting pronounced anti-proliferative and apoptosis-inducing properties

Synthesis of indole-derived allocolchicine congeners exhibiting pronounced anti-proliferative and apoptosis-inducing properties Synthesis and biological evaluation of novel non-racemic indole-containing allocolchicinoids Synthesis and cytostatic properties of polyfunctionalized furanoallocolchicinoids Synthetic 2-Aroylindole Derivatives as a New Class of Potent Tubulin-Inhibitory, Antimitotic Agents Synthesis and Biological Evaluation of Furanoallocolchicinoids Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents Discovery of dihydrofuranoallocolchicinoids - Highly potent antimitotic agents with low acute toxicity Allocolchicinoids bearing a Michael acceptor fragment for possible irreversible binding of tubulin Design, synthesis and biological evaluation of indole-based [1,2,4]triazolo[4,3-a] pyridine derivatives as novel microtubule polymerization inhibitors 4- and 5-Aroylindoles as Novel Classes of Potent Antitubulin Agents