Original Vinca Derivatives: From P-Glycoprotein Substrates to P-Glycoprotein Inhibitors

Original Vinca Derivatives: From P-Glycoprotein Substrates to P-Glycoprotein Inhibitors Vinflunine (20′,20′-difluoro- 3′,4′-dihydrovinorelbine), a novel Vinca alkaloid, which participates in P-glycoprotein (Pgp)-mediated multidrug resistance in vivo and in vitro Vinflunine (20′,20′-difluoro- 3′,4′-dihydrovinorelbine), a novel Vinca alkaloid, which participates in P-glycoprotein (Pgp)-mediated multidrug resistance in vivo and in vitro Vinblastine 20′ Amides: Synthetic Analogues That Maintain or Improve Potency and Simultaneously Overcome Pgp-Derived Efflux and Resistance Arylmethyloxyphenyl Derivatives:  Small Molecules Displaying P-Glycoprotein Inhibition Structure−activity relationship study of novel 2-aminobenzofuran derivatives as P-glycoprotein inhibitors Potent P-glycoprotein inhibition of emodin derivative: synthesis and biological evaluation Flavonoid-Related Modulators of Multidrug Resistance:  Synthesis, Pharmacological Activity, and Structure−Activity Relationships New triazine derivatives as potent modulators of multidrug resistance Synthesis and structure–activity relationship studies of cytotoxic vinorelbine amide analogues