Expanding the tetrahydroquinoline pharmacophore

Bioorganic & Medicinal Chemistry Letters
2017.0

Abstract

Tetrahydroquinoline is a privileged scaffold with a large number of biological applications. The tetrahydroquinoline pharmacophore has been expanded to yield 34 compounds. Biological screening of these compounds led to the identification of tetrahydroquinoline as neurotropic agents not reported earlier.

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