Computer-Aided Selective Optimization of Side Activities of Talinolol

Computer-Aided Selective Optimization of Side Activities of Talinolol Selective Optimization of Side Activities:  Another Way for Drug Discovery Discovery of soluble epoxide hydrolase inhibitors through DNA-encoded library technology (ELT) Evaluation of structure-derived pharmacophore of soluble epoxide hydrolase inhibitors by virtual screening Design, synthesis and biological evaluation of 4-(1-(4(sulphanilamide)phenyl)-3-(methyl)-1H-pyrazol-5-yl)dine urea and N-acyl derivatives as a soluble epoxide hydrolase inhibitors Ligand-based optimization to identify novel 2-aminobenzo[d]thiazole derivatives as potent sEH inhibitors with anti-inflammatory effects Structure−Activity Relationships of Cycloalkylamide Derivatives as Inhibitors of the Soluble Epoxide Hydrolase Novel soluble epoxide hydrolase inhibitors with a dihydropyrimidinone scaffold: design, synthesis and biological evaluation Discovery of a Highly Potent, Selective, and Bioavailable Soluble Epoxide Hydrolase Inhibitor with Excellent Ex Vivo Target Engagement Can We Make Small Molecules Lean? Optimization of a Highly Lipophilic TarO Inhibitor