Small Molecule Mitochondrial Uncouplers and Their Therapeutic Potential

Small Molecule Mitochondrial Uncouplers and Their Therapeutic Potential 6-Amino[1,2,5]oxadiazolo[3,4-b]pyrazin-5-ol Derivatives as Efficacious Mitochondrial Uncouplers in STAM Mouse Model of Nonalcoholic Steatohepatitis [1,2,5]Oxadiazolo[3,4-b]pyrazine-5,6-diamine Derivatives as Mitochondrial Uncouplers for the Potential Treatment of Nonalcoholic Steatohepatitis Synthesis of prenylated quinolinecarboxylic acid derivatives and their anti-obesity activities An Underlying Mechanism of Dual Wnt Inhibition and AMPK Activation: Mitochondrial Uncouplers Masquerading as Wnt Inhibitors The medicinal chemistry of mitochondrial dysfunction: a critical overview of efforts to modulate mitochondrial health Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes Identification of small-molecule urea derivatives as PTPC modulators targeting the c subunit of F1/Fo-ATP synthase Identification of small molecules that bind to the mitochondrial protein mitoNEET Mammea E/BB, an Isoprenylated Dihydroxycoumarin Protonophore That Potently Uncouples Mitochondrial Electron Transport, Disrupts Hypoxic Signaling in Tumor Cells