Discovery of pyrazolone spirocyclohexadienone derivatives with potent antitumor activity

Discovery of pyrazolone spirocyclohexadienone derivatives with potent antitumor activity Synthesis of spiro-pyrrolizidine: Crystal structure and anticancer activity Synthesis and anticancer activity evaluation of naphthalene-substituted triazole spirodienones Design, synthesis, and antitumor activity evaluation of novel acyl sulfonamide spirodienones Design, synthesis, and antitumor study of a series of novel 1-Oxa-4-azaspironenone derivatives Design and synthesis of novel 2′-hydroxy group substituted 2-pyridone derivatives as anticancer agents Novel spiropyrazolone antitumor scaffold with potent activity: Design, synthesis and structure–activity relationship Synthesis and anticancer activity of novel spiro-isoxazoline and spiro-isoxazolidine derivatives of α-santonin Design and synthesis of novel pyrazolo[1,5-a]pyrimidine derivatives bearing nitrogen mustard moiety and evaluation of their antitumor activity in vitro and in vivo Development of novel bis-pyrazole derivatives as antitumor agents with potent apoptosis induction effects and DNA damage