Columnaristerol A, a novel 19-norsterol from the Formosan octocoral Nephthea columnaris

Bioorganic & Medicinal Chemistry Letters
2016.0

Abstract

Columnaristerol A (1), a rare natural 19-norsterol possessing a 10β-hydroxy group was isolated from the Formosan octocoral Nephthea columnaris, and its structure was elucidated by spectroscopic methods. Sterol 1 was found to be a cytotoxic agent that exhibited in vitro moderate cytotoxic activity against MOLT-4 and SUP-T1 human leukemia-lymphoma cell lines.

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