From Seeds ofApium graveolensLinn. to a Cerebral Ischemia Medicine: The Long Journey of 3-n-Butylphthalide

Journal of Medicinal Chemistry
2020.0

Abstract

3-n-Butylphthalide (NBP) as well as its derivatives and analogues (NBPs), in racemic or enantiomerically pure forms, possess potent and diverse pharmacological properties and have shown a great potential therapeutic interest for many human conditions, especially for cerebral ischemia. This Perspective outlines the synthesis and therapeutic applications of NBPs.

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