Discovery and Characterization of a PKS–NRPS Hybrid in Aspergillus terreus by Genome Mining

Journal of Natural Products
2020.0

Abstract

Fungal polyketide synthase-nonribosomal peptide synthetase (PKS-NRPS) hybrids have been characterized to produce polyketide-amino acid compounds with striking structural features and biological activities. In this study, a PKS-NRPS hybrid enzyme was found in

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