Pyranonigrin E: A PKS‐NRPS Hybrid Metabolite from Aspergillus niger Identified by Genome Mining

Pyranonigrin E: A PKS‐NRPS Hybrid Metabolite from <i>Aspergillus niger</i> Identified by Genome Mining Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans Three Acyltetronic Acid Derivatives: Noncanonical Cryptic Polyketides from <i>Aspergillus niger</i> Identified by Genome Mining Characterization of a polyketide synthase in Aspergillus niger whose product is a precursor for both dihydroxynaphthalene (DHN) melanin and naphtho-γ-pyrone Discovery and Characterization of a PKS–NRPS Hybrid in <i>Aspergillus terreus</i> by Genome Mining Elucidation of Pyranonigrin Biosynthetic Pathway Reveals a Mode of Tetramic Acid, Fused γ-Pyrone, and <i>exo</i>-Methylene Formation Biosynthesis of Amino Acid Derived α-Pyrones by an NRPS–NRPKS Hybrid Megasynthetase in Fungi A chemical epigenetics approach for engineering the in situbiosynthesis of a cryptic natural product from Aspergillus niger Multifactorial Induction of an Orphan PKS-NRPS Gene Cluster in Aspergillus terreus Nigerazine B, a New Metabolite from<i>Aspergillus niger</i>Screening, Isolation, and Chemical and Biological Properties