Three new cyclic peptides, delavayins A-C (1-3), were isolated from the roots of Stellaria delavayi. The structures of 1-3, cyclo(-Gly-Ser-γ-hydroxy Ile-Phe-Phe-Ala-) (1), cyclo(-Gly-Ser-Ile-Phe-Phe-Ala-) (2), cyclo(-Gly-Tyr-Tyr-Tyr-Pro-Val-Pro-) (3), were elucidated from spectroscopic evidence and by chemical degradation. As part of a continuing investigation on new biologically active cyclic peptides from higher plants, we have previously isolated several cyclic peptides; yunnanins from the roots of Stellaria yunnanensis, 2-4 pseudostellarins from the roots of Pseudostellaria heterophylla, 5-8 dichotomins from the roots of Stellaria dichotoma var. lanceolata, 9,10 and segetalins from the roots of Vaccaria segetalis.11-13 All of these plants belong to the family Caryophyllaceae. As a result of the investigation of Stellaria delavayi Franch., which also belongs to the same family, we have isolated three new cyclic peptides, delavayins A-C (1-3). In this paper, we describe the isolation and structure elucidation of 1-3.