Separation of E-Z isomeric macrocyclic spermine alkakoids of Verbascum pseudonobile and Verbascum phoeniceum and of their derivatives using thin-layer chromatography

Journal of Chromatography A
1996.0

Abstract

Twelve E-Z isomeric pairs of Verbascum pseudonobile Stoj. et Stef. and Verbascum phoeniceum L. (Scrophulariaceae) macrocyclic spermine alkaloids and of related compounds and six related dihydro derivatives were studied by TLC on silica in nine systems and on alumina in four systems. In most cases the Z isomers exhibited higher retention than their E counterparts. Four E-Z isomeric pairs of cinnamic acid amides were studied for comparison.

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