Macrocyclic Spermine Alkaloids fromVerbascum: The (E/Z)-Isomeric Pairs (−)-(S)-Verbasitrine/(−)-(S)-Isoverbasitrine and (+)-(S)-Verbametrine/(+)-(S)-Isoverbametrine: Isolation, Structure Elucidation, and Synthesis

Helvetica Chimica Acta
1999.0

Abstract

The isolation and structure elucidation of the 17-membered macrocyclic spermine alkaloid!, (-)-(S)-verbasitrine (2). (-_-(S)-isoverbasitrine (4), (+)-(S)-verbametrine (6), and (+)-(S)-isoverbametrine (8) is presented. The synthesis of their racemates is described.

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