The trunk wood of L~ar~a macrophylla (A C Smith) Kosterm (Lauraceae) contains, m addition to sltosterol, terpene (borneol) and sesqulterpene (nerohdol, elemol) alcohols, a novel neohgnan, macrophyllm, for which the structure of 3-allyl-8-hydroxy-l,5-dlmethoxy-7-methyl-4(or 2)-oxo-6-(3'.4'-methylenedioxy-5'-methoxyphenyl)-blcyclo [3,2,1] act-2(or 4)-ene 1s proposed