Alkaloids of leuconotis griffithii and L. Eugenifolia (Apocynaceae)

Tetrahedron
1989.0

Abstract

Leuconotis griffithii and L. eugenifolia provided a variety of Strychnos and Aspidosperma-Hunteria alkaloids as well as novel ring-opened indole alkaloids including leuconolam (6), rhazinilam (8) and 5,21-dihydrorhazinilam (9). Facile acid and base reactions of leuconolam lead to ring reclosure products. Physical and spectral data of norfluorocurarine (1a), norfluorocurarine-Nb-oxide (1b), eburnamine (2), kopsinine (5) and epileuconolam (7) as well as some derivatives of leuconolam are also provided. © 1989.

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