Absolute Configuration of Hydroxycitric Acid Produced by Microorganisms

Bioscience, Biotechnology, and Biochemistry
2006.0

Abstract

Optical resolution for (2S,3R) and (2R,3S)-hydroxycitric acid (HCA) enantiomers was developed using chiral column chromatography. HCA from Bacillus megaterium G45C and Streptomyces sp. U121, newly isolated in our previous study, was analyzed to determine the absolute configuration. These results indicate that both strains generate optically pure (2S,3R)-hibiscus type HCA enantiomer.

Knowledge Graph

Similar Paper

Absolute Configuration of Hydroxycitric Acid Produced by Microorganisms
Bioscience, Biotechnology, and Biochemistry 2006.0
Production of Hydroxycitric Acid by Microorganisms
Bioscience, Biotechnology, and Biochemistry 2005.0
Genome shuffling of Streptomyces sp. U121 for improved production of hydroxycitric acid
Applied Microbiology and Biotechnology 2007.0
The Absolute Configuration of 1-(3‘,4‘-Dihydroxycinnamoyl)cyclopentane-2,3-diol from the Amazonian Tree <i>Chimarrhis </i><i>t</i><i>urbinata</i>
Journal of Natural Products 2006.0
The isolation and absolute configuration of (1S,2S,3R)-4- Hydroxymethylcyclopent-4-ene-1,2,3-triol: A putative intermediate in the biosynthesis of aristeromycin by Streptomyces citricolor
Tetrahedron Letters 1993.0
Characterization of medium chain length (R)-3-hydroxycarboxylic acids produced by Streptomyces sp. JM3 and the evaluation of their antimicrobial properties
World Journal of Microbiology and Biotechnology 2012.0
Chiral Dihydroxylation of Acronycine:  Absolute Configuration of Natural cis-1,2-Dihydroxy-1,2-dihydroacronycine and Cytotoxicity of (1R,2R)- and (1S,2S)-1,2-Diacetoxy-1,2-dihydroacronycine
Journal of Natural Products 1999.0
Structure and absolute configuration of new acidic metabolites from Stachys ehrenbergii
Tetrahedron Letters 2011.0
Four New Antibacterial Xanthones from the Marine-Derived Actinomycetes Streptomyces caelestis
Marine Drugs 2012.0
Four New Antibacterial Xanthones from the Marine-Derived Actinomycetes Streptomyces caelestis
Marine Drugs 2012.0