Polyenoic acid piperideides and other alkamides from Achillea millefolium

Phytochemistry
1989.0

Abstract

From the lipophilic extract of subterranean parts of Achilles millefolium s.str. 17 different alkamides together with (+)-sesamin were separated by CC, MPLC, TLC, and identified by spectroscopic methods. The stereochemistries of the fully conjugated decatetraenoic acid piperideides were established for the first time by using the lanthanide-induced shift technique. Besides a rare decadienoic acid tyramide and the corresponding novel p-methoxy derivative the amide pattern is especially characterized by the dominating olefinic piperideides.

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