Structure of malolactomycins A and B, novel 40-membered macrolide antibiotics

Tetrahedron
1993.0

Abstract

Three 9-acridone alkaloids, melicopicine, tecleanthine and 6-methoxy tecleanthine were isolated from the bark of Teclea trichocarpa. Melicopicine and tecleanthine exhibited mild antifeedant activity against the African armyworm, Spodoptera exempta. All the three alkaloids showed antimicrobial activity against the fungus, Cladosporium cucumerinum and the bacterium, Bacillus subtilis.

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