A chemical epigenetics approach for engineering the in situbiosynthesis of a cryptic natural product from Aspergillus niger

A chemical epigenetics approach for engineering the in situbiosynthesis of a cryptic natural product from Aspergillus niger New Natural Products from the Sponge-Derived Fungus<i>Aspergillus n</i><i>iger</i> New Natural Products from the Sponge-Derived Fungus<i>Aspergillus n</i><i>iger</i> Pyranonigrin E: A PKS‐NRPS Hybrid Metabolite from <i>Aspergillus niger</i> Identified by Genome Mining Reappraising the Structures and Distribution of Metabolites from Black Aspergilli Containing Uncommon 2-Benzyl-4<i>H</i>-pyran-4-one and 2-Benzylpyridin-4(1<i>H</i>)-one Systems Nigerazine B, a New Metabolite from<i>Aspergillus niger</i>Screening, Isolation, and Chemical and Biological Properties Nigerapyrones A–H, α-Pyrone Derivatives from the Marine Mangrove-Derived Endophytic Fungus <i>Aspergillus niger</i> MA-132 Elucidation of Pyranonigrin Biosynthetic Pathway Reveals a Mode of Tetramic Acid, Fused γ-Pyrone, and <i>exo</i>-Methylene Formation Structure and Total Synthesis of Aspernigerin: A Novel Cytotoxic Endophyte Metabolite Structure and Total Synthesis of Aspernigerin: A Novel Cytotoxic Endophyte Metabolite