Four known aporphine alkaloids, boldine, norboldine, laurotetanine and lindecarpine were isolated from the bark of Phoebe grandis. The leaves yielded two new alkaloids belonging to the proaporphine-tryptamine dimers series, phoebegrandines A and B. The structure of the new compounds was elucidated by spectral methods. (C) 1997 Elsevier Science Ltd. All rights reserved.