<jats:p> The bark of Hernandiapeltata Meissner (Hernandiaceae) has yielded four new dimeric alkaloids, namely (+)-6-northalicarpine 6, (+)-thalicarpine 2′-N-oxide 10, (+)-hebridamine 11, and (+)-vilaportine 12. Hebridamine is the first example of a benzylisoquinoline-phenanthrene dimer and (+)-vilaportine is a dimer with an oxoaporphinium zwitterionic moiety. The 6a,7-dehydrothalmelatine 9, previously known as a synthetic compound, has been isolated from a natural source for the first time. The possibility of a biogenetic relationship between (+)-vanuatine and (+)-thalicarpine 7 is considered.