From the combined chloroform-extracted material of the epigeal part of Korolkowia sewerzowii Regel the new alkaloid sevedamine has been isolated, with mp 256-258°C (acetone) [α]D +3.6° (c 1.25; ethanol), C27H45NO3. On the basis of the results of a study of the UV, IR, PMR, and mass spectra of sevedamine and also performance of a transition to the known alkaloid korseverilinedione it has been established that sevedamine has the structure and configuration of 3β,6α,14α-trihydroxycevanine. © 1987 Plenum Publishing Corporation.