Structure of Sevedinine

Chemistry of Natural Compounds
2004.0

Abstract

The new steroidal alkaloid sevedinine was isolated from the aerial part of Korolkovia severtzovii. The structure of sevedinine was established as 6beta,12alpha-dihydroxy-5alpha-cevanin-3-one using spectral data, chemical transformations, and an x-ray structure analysis. The location of the tertiary hydroxyl in ten cevine alkaloids from Korolkovia severtzovii was corrected based on the results.

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