Beauvericin K, a New Antifungal Beauvericin Analogue from a Marine-derived Fusarium sp

Natural Product Communications
2016.0

Abstract

<jats:p> Chemical investigation of a Chinese collection of a marine-derived fungus, Fusarium sp., led to the characterization of beauvericin K, a new analogue of beauvericin. The structure of the new compound was elucidated by detailed spectroscopic analysis, including 1D and 2D NMR methods, and HRMS. Beauvericin K showed significant activity against the yeast Candida albicans with an IC<jats:sub>50</jats:sub> value of 6.25 μg/mL.

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