<jats:p> Chemical investigation of a Chinese collection of a marine-derived fungus, Fusarium sp., led to the characterization of beauvericin K, a new analogue of beauvericin. The structure of the new compound was elucidated by detailed spectroscopic analysis, including 1D and 2D NMR methods, and HRMS. Beauvericin K showed significant activity against the yeast Candida albicans with an IC<jats:sub>50</jats:sub> value of 6.25 μg/mL.