Arenastatin A, a potent cytotoxic depsipeptide from the okinawan marine sponge Dysidea arenaria

Tetrahedron Letters
1994.0

Abstract

Arenastatin A (1) has been isolated from the Okinawan marine sponge Dysidea arenaria and the chemical structure including parts of the absolute configurations elucidated. Arenastatin A (1) is a cyclic didepsipeptide and exhibited extremely potent cytotoxicity against KB cells at IC50 5 pg/ml.

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