Senecio erraticus Berthol grown in Transcaucasia and Transcarpathia has not been studied for its alkaloid content, while a number of alkaloids including senecionine have been isolated from the epigeal part of the plant growing in Czechoslovakia. By ethanolic extraction of the epigeal part of S. erraticus collected in the flowering phase in July 1971 in the environs of Kobuleti, Adzhar ASSR, 0.18% of combined alkaloids and 0.05% of a mixture of bases from N-oxides were isolated. The two fractions were similar chromatographically and studied together. Separation was performed on an Al₂O₃ column with eluents like ether-chloroform mixtures and chloroform-methanol. Alkaloid (I) (mp 229-231°C, M⁺ 335) was identified as senecionine by mixed melting point, consistent Rf values, IR, UV, and mass spectra with an authentic sample. Alkaloid (II) (mp 212-222°C, [α]ᴅ +11°, M⁺ 381) was identified as otosenine by spectral data (no UV absorption, IR bands at 1700, 1760, 1580 cm⁻¹, mass spectrum peaks for otonecine ethers, NMR signals) and mixed melting point. Alkaloid (III) (mp 192-193°C) was identified as floridanine by spectral features (no UV absorption, IR bands for hydroxy, ester, and trans-annular carbonyl-nitrogen groups, mass spectrum molecular ion m/e 441, NMR signals of five methyl groups). Thus, three alkaloids have been isolated from S. erraticus growing in Transcaucasia and identified: otosenine (the main component), senecionine, and floridanine.