713A, a New Metabolite Isolated from a Fungal Strain 713

Chemical and Pharmaceutical Bulletin
2008.0

Abstract

A new compound named 713A was isolated from the fermentation broth of a fungal strain 713. The structure of 713A was elucidated by spectroscopic methods. In the screening for interleukin-6 (IL-6) receptor antagonist, 713A exhibited inhibitory activity to the binding of IL-6 and IL-6 receptor with an IC50 value of 8.6 microM.

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