Studies on new aminoglycoside antibiotics, istamycins, from an actinomycete isolated from a marine environment. I. The use of plasmid profiles in screening antibiotic-producing streptomycetes.

The Journal of Antibiotics
1980.0

Abstract

Plasmid profiles were used to screen streptomycetes for production of new antibiotics. Among about 100 strains isolated from sea muds, an isolate designated SS-939 was revealed to harbor several plasmids of different sizes, and to produce istamycins, new aminoglycoside antibiotics. Based on the characteristics of the strain, a new Streptomyces species is proposed: S. tenjimariensis.

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