Echinoclathrines A–C: A new class of pyridine alkaloids from an Okinawan sponge, Echinoclathria sp.

Tetrahedron
1999.0

Abstract

Echinoclathrines A-C (3 - 5) have been isolated from an Okinawan sponge, Echinoclathria sp. and the structures elucidated by interpretation of spectral data These compounds are a new class of pyridine alkaloids possessing an 4-aryl-2-methylpyridine moiety as a common structural element. Echinoclathrines A and B exhibited weak immunosuppressive activity in a mixed lymphocyte reaction assay. (C) 1999 Elsevier Science Ltd. All rights reserved.

DOI： 10.1016/S0040-4020(99)00022-8

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