Microsclerodermins F–I, Antitumor and Antifungal Cyclic Peptides from the Lithistid Sponge Microscleroderma sp.

Tetrahedron
2000.0

Abstract

Four new cyclic peptides, microsclerodermins F±I (6±9), were isolated from the deep water lithistid sponge Microscleroderma sp. from Palau. Their structures, which incorporate an unusual long chain b-amino acid, were elucidated using spectroscopic methods and chemical degradation.

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