Discodermins F-H, cytotoxic and antimicrobial tetradecapeptides from the marine sponge Discodermia kiiensis: Structure revision of discodermins A-D

Tetrahedron
1994.0

Abstract

Three new cytotoxic and antimicrobial peptides, discodermins F (6), G (7), and H (8), have been isolated from the marine sponge Discodermia kiiensis. The structures of 6-8 were determined by interpretation of spectral data and chemical degradation. Structures of discodermins A-D were revised on the basis of NMR data and protein sequence analysis.

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