<jats:p>Laportoside A (1), a new cerebroside, and a new ceramide named laportomide A (2), have been isolated from Laportea ovalifolia. Their structures were determined by comprehensive analyses of their 1D, 2D NMR, and HREIMS spectral data. The remaining two known compounds were identified as β -sitosterol acetate, and β -sitosterol glucopyranoside.