Repeated chromatography of the nonquaternary alkaloid fraction of an extract of the bark of Daphnandra dielsii Perk. (Monimiaceae) over silica gel afforded the new bisbenzylisoquinoline alkaloid (-)-nortenuipine-2'β-N-oxide (1) which was characterized by a consideration of physicochemical data and reduction to (-)-nortenuipine. In addition, seven other bisbenzylisoquinoline alkaloids of known structure were isolated and identified.