Two new compounds, spatosterol (1) and thyminol (2) were isolated from Spatoglossum variabile and colonial Zoanthid, respectively. Three known compounds, 2-deoxyinosine (3), 2-deoxythymidine (4) and hexadecylhexadecanoate (5) were also isolated for the first time from the methanolic extract of the colonial Zoanthid.