As a part of an investigation of the phytochemistry of Atriplex nunmularia Lindley (Chenopcdiaceae), a 2-3 m high shrub common in the Nile Delta and oases of Egypt ( l), we isolated the two monodesmosidic saponins hederagenin-3-0-~-D-glucuronopyranoside and oleanolic acid-3-0-~-D-glucuronopyranoside (calenduloside E) in a yield of 2% of dried plant material for each of the two glucuronides. Both of the sapcnins have previously been reported to be potent molluscicides (2). Thus, A. nrrmmularia might be a potent tool for controlling schistosomiasis, which is considered to be one of the most significant and rapidly spreading parasitic diseases in many tropical and subtropical parts of Africa, the Middle East, the Far East, some Caribean Islands, and many parts of South America (3-5).