A Nitro Analogue of Staurosporine and Other Minor Metabolites Produced by a Streptomyces longisporoflavus Strain.

A Nitro Analogue of Staurosporine and Other Minor Metabolites Produced by a Streptomyces longisporoflavus Strain. Further Minor Metabolites of Staurosporine Produced by a Streptomyces longisporofiavus Strain. Further Minor Metabolites of Staurosporine Produced by a Streptomyces longisporofiavus Strain. 3'-Demethoxy-3'-hydroxystaurosporine, a Novel Staurosporine Analogue Produced by a Blocked Mutant. Production of the Staurosporine Aglycon K-252c with a Blocked Mutant of the Staurosporine Producer Strain Streptomyces longisporoflavus and by Biotransformation of Staurosporine with Streptomyces mediocidicus ATCC 13279. The Shurosporine Producing Strain Streptomyces longisporoflavus Produces Metabolites Related to K-252a. Proposal for Biosynthetic Intermediates of K-252a. A new staurosporine analog from ActinomycetesStreptomycessp. (172614) A new inhibitor of protein kinase C, RK-1409 (7-oxostaurosporine). II. Fermentation, isolation, physico-chemical properties and structure. Bioactive staurosporine derivatives from the Streptomyces sp. NB-A13 MLR-52,(4'-dementhylamino-4',5'-dihydroxystaurosporine), a new inhibitor of protein kinase C with immunosuppressive activity.