Isolation and structure elucidation of new salfredin-type metabolites fromCrucibulum laeve DSM 1653 and DSM 8519

Journal of Basic Microbiology
1999.0

Abstract

New salfredin-type chromene and benzofurane metabolites were isolated from submerged cultures of the fungal strains Crucibulum laeve DSM 1653 and C. laeve DSM 8519. The structures were elucidated on the basis of UV-VIS spectroscopic, mass spectrometric and NMR spectroscopic evidence. Here we report the structures of these new metabolites as new representatives of the salfredin family of fungal metabolites and discuss their possible role as intermediates and shunt metabolites of a general biosynthetic pathway leading to A-, B- and C-type salfredins.

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