New Antifungal Bithienylacetylenes from Blumea obliqua

Journal of Natural Products
1995.0

Abstract

Two new bioactive bithienylacetylenes isolated from Blumea obliqua have been characterized as 5'-methyl-5-[4-(3-methyl-1-oxobutoxy)-1-butynyl]-2,2'- bithiophene [1] and 5'-hydroxymethyl-5-[butyl-3-en-1-yn]-2,2'-bithiophene isovaleroxy ester [2], respectively. Compounds 1 and 2 showed antifungal activity against Epidermophyton floccosum and Pleurotus ostreatus.

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